Sugar acids and derivatives
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 50 MG
Glucuronic acid sodium is a polysaccharide that shows anti-inflammatory activity, helps heal ulcerative colitis, and improves the intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin. It also modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones.
- Shows anti-inflammatory activity
- Helps heal ulcerative colitis
- Improves intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin
- Modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones
Medchemexpress LLC Bet bromodomain inhibitor 4 | 2407658-41-5 | ≥98.0% | 518.59 g/mol | C27H31FN8O2 | 10 MG
BET bromodomain inhibitor 4 is a small-molecule inhibitor of BET family bromodomain epigenetic reader domains supplied for research use as a 10 mg powder. It is used in preclinical studies to probe BET-mediated epigenetic regulation and assay bromodomain interactions.
- Inhibits BET bromodomain activity.
- Intended for research use only.
- Supplied as a 10 mg powder for laboratory applications.
- Target: epigenetic reader domain (BET bromodomain).
- CAS number: 2407658-41-5.
- Molecular formula: C27H31FN8O2; molecular weight: 518.59 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC Beta-D-glucopyranosyl nitromethane | 81846-60-8 | 99.5% | C7H13NO7 | 25 MG
Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane, presented as a salt of a strongly basic anion exchanger in the OH cycle. This chemical is intended for research use only, serving as a laboratory chemical and for the manufacture of substances.
- Glycosyl derivative of nitromethane.
- Presented as a salt of a strongly basic anion exchanger in the OH cycle.
- Suitable for laboratory chemical applications.
- Used in the manufacture of substances.
Medchemexpress LLC DCP-LA | 28399-31-7 | 98.0% | 308.50 | 25 MG
DCP-LA is a linoleic acid derivative that selectively and directly activates PKCε. It also activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. Additionally, DCP-LA inhibits the activation of caspase-3/-9 and helps protect neurons from oxidative stress-induced apoptosis.
- Selectively and directly activates PKCε
- Activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)
- Inhibits protein phosphatase-1 (PP-1)
- Stimulates AMPA receptor exocytosis
- Inhibits activation of caspase-3/-9
- Helps protect neurons from oxidative stress-induced apoptosis
- Facilitates hippocampal synaptic transmission
- Exhibits protective effect against ischemic brain damage
Medchemexpress LLC D-γ-glutamyl-D-glutamic acid | 4553-17-7 | 98.9% | 276.24 g/mol | C10H16N2O7 | 25 MG
D-γ-Glutamyl-D-glutamic acid is a D-stereoisomer dipeptide composed of γ-linked glutamyl and glutamic acid residues. It is supplied as a research-grade reagent for biochemical and pharmaceutical studies, suitable for use as an analytical standard, control compound, or experimental reagent.
- Peptide composition: D-γ-linked glutamyl and glutamic acid.
- Molecular weight approximately 276.24 g/mol.
- High purity suitable for research applications.
- Available in multiple small pack sizes for analytical use.
- Used as a control or reference in biochemical assays.
Medchemexpress LLC Integrin alpha V bet 10ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
Medchemexpress LLC Beta-D-glucuronide-pNP-carbonate | 894095-98-8 | MFCD31715405 | >96.0% | 913.83 g/mol | C45H43N3O18 | 50 MG
β-D-glucuronide-pNP-carbonate is a glycosidase-cleavable antibody-drug conjugate (ADC) linker that contains a para-nitrophenyl carbonate reactive handle and a β-D-glucuronide cleavable trigger. It is supplied as a solid for research use and is designed to release payloads upon enzymatic cleavage by glucuronidase.
- Glycosidase-cleavable linker for targeted payload release.
- Para-nitrophenyl carbonate reactive handle for payload attachment.
- Solid form suitable for standard laboratory handling.
- Available in small research-scale quantities for synthesis work.
- Intended for research use only; not for clinical or human use.
Medchemexpress LLC Chmfl-pi4k-127 | 2377604-81-2 | 99.9% | 402.85 g/mol | C18H15ClN4O3S | 10 MG
CHMFL-PI4K-127 is a potent, selective Plasmodium falciparum phosphatidylinositol 4-kinase (PfPI4K) inhibitor provided for research use. It exhibits sub-nanomolar enzymatic potency and cellular antimalarial activity, and is supplied at high chemical purity suitable for in vitro and in vivo studies.
- Potent PfPI4K inhibition (IC50 ~0.9 nM).
- Demonstrated cellular antimalarial activity (EC50 ~25.1 nM).
- High chemical purity for reliable experimental results (>99.9%).
- Available in research-scale quantities for assay development.
- Soluble in DMSO for standard compound handling and dosing.
AdipoGen 3-oxo-C11-L-HSL
Chemical. CAS 216596-70-2. Formula C15H25NO4. MW 283.4. Synthetic. N-3-Oxoundecanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. Numerous species of bacteria employ 3OC11-HSL in cell-to-cell communication. Shown to have immune suppressive activity, inhibiting murine and human leucocyte proliferation.
AdipoGen 3-Oxo-C9-L-HSL
Chemical. CAS 441350-70-5. Formula C13H21NO4. MW 255.31. N-3-Oxononanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Medchemexpress LLC D-Nmappd | 35922-06-6 | MFCD08062172 | 99.7% | 422.6 g/mol | C23H38N2O5 | 25MG
D-NMAPPD ((1R,2R)-B13) is a research-grade small-molecule acid ceramidase inhibitor that modulates NMDA receptor properties by enhancing endogenous ceramide production. It is used in biochemical and neurological research and has been reported to show anticancer activity in experimental studies. The compound is supplied in milligram-scale quantities with high reported purity suitable for laboratory applications.
- Inhibits acid ceramidase activity.
- Modulates NMDA receptor properties by enhancing endogenous ceramide production.
- Reported anticancer activity in experimental studies.
- High purity (~99.7%) suitable for research use.
- Molecular formula C23H38N2O5; molecular weight 422.6 g/mol.
- Available in milligram-scale package sizes for laboratory experiments.
Medchemexpress LLC 4-Methylumbelliferyl | 124223-99-0 | 10MG
4-Methylumbelliferyl 2-acetamido-2-deoxy- -D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of -galactosidase 4-Methylumbelliferyl 2-acetamido-2-deoxy- -D-galactopyranoside is used to analyze enzyme activity in various biological samples helping scientists gain insight into the function of the enzyme in vivo 4-Methylumbelliferyl 2-acetamido-2-deoxy- -D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme
Sigma Aldrich Fine Chemicals Biosciences Acetobromo alpha D glucose100G
Acetobromo alpha D glucose100G
Medchemexpress LLC IL-1RA/IL-1F3 Porci 50ug | 50ug
IL-1RA/IL-1F3 proteins are powerful anti-inflammatory antagonists in the interleukin 1 family specifically targeting the pro-inflammatory cytokines IL1B and IL1A This protein counteracts the inflammatory effects of IL1 playing a critical role in preventing immune dysregulation and preventing uncontrolled systemic inflammation triggered by a variety of innate irritants including pathogens IL-1RA/IL-1F3 Protein Porcine is the recombinant Porcine-derived IL-1RA/IL-1F3 protein expressed by E coli with tag free
Medchemexpress LLC Integrin alpha V bet 5ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively